The Physiological Basis of Diuretic Action

Laboratory experience for understanding the physiological basis of diuretic therapy.

A combined lecture and laboratory experience was designed to enhance medical school students' understanding of the physiological basis of diuretic therapy. Studies are performed by students in anesthetized dogs to determine the effects of four clinically useful diuretics on renal function. The objective of the experience is to 1) learn the mechanisms of action, clinical indications, and adverse...

Physiological and molecular basis of thyroid hormone action.

Thyroid hormones (THs) play critical roles in the differentiation, growth, metabolism, and physiological function of virtually all tissues. TH binds to receptors that are ligand-regulatable transcription factors belonging to the nuclear hormone receptor superfamily. Tremendous progress has been made recently in our understanding of the molecular mechanisms that underlie TH action. In this revie...

The Physiological Basis of Physiotherapy

THIS is the third edition of an American book written for housemen and surgical trainees and it will inevitably be compared with the well-known British equivalent-Pye's Surgical Handicraft. The book is beautifully produced and well illustrated covering a wide field of surgical activity from the tying of knots to cancer chemotherapy. The clarity of the description and illustration of minor surgi...

Physiological Basis of Exercise

Biochemical oxygen activation as the basis for the physiological action of tetrachlorodecaoxide (TCDO).

Oxidation of methionine, 4-(methylthio)-2-oxobutyric acid (KMB), or 1-aminocyclopropane carbonic acid (ACC) are indicator reactions for activated oxygen species such as singlet oxygen (1O2), OH.-radical like oxidants, superoxide anion (O2.-), hydrogen peroxide (H2O2) or activated hemo-iron complexes like peroxidase- or catalase-"compound I". Methionine is oxidized by OH. as well as by 1O2 formi...